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Rabbit Anti-Peroxiredoxin-4 antibody
Rabbit Anti-Peroxiredoxin-4 antibody
Antioxidant enzyme 372;Antioxidant enzyme AOE372;AOE37 2;AOE37-2;AOE372;EC 1.11.1.15;Peroxiredoxin IV;Peroxiredoxin-4;Peroxiredoxin4;PRDX 4;Prdx4;PRDX4_HUMAN;PRX 4;Prx IV;Prx-IV;PRX4;PrxIV;Thioredoxin dependent peroxide reductase A0372;Thioredoxin Peroxid
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  • NO.:SL23510R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human,Mouse,(predicted: Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
    Applications:WB ELISA
    concentration:1mg/ml
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Details

Product Name Peroxiredoxin-4
Chinese Name 过氧化物还原酶4抗体
Alias Antioxidant enzyme 372; Antioxidant enzyme AOE372; AOE37 2; AOE37-2; AOE372; EC 1.11.1.15; Peroxiredoxin IV; Peroxiredoxin-4; Peroxiredoxin4; PRDX 4; Prdx4; PRDX4_HUMAN; PRX 4; Prx IV; Prx-IV; PRX4; PrxIV; Thioredoxin dependent peroxide reductase A0372; Thioredoxin Peroxidase (Antioxidant Enzyme); Thioredoxin peroxidase; Thioredoxin peroxidase AO372; Thioredoxin-dependent peroxide reductase A0372; TRANK.  
Research Area Cell biology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, Mouse,  (predicted: Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 27kDa
Cellular localization cytoplasmic Secretory protein 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human Peroxiredoxin-4: 31-130/271 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB. [provided by RefSeq, Jul 2008]

Function:
Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.

Subcellular Location:
Cytoplasm. Secreted.

Similarity:
Belongs to the ahpC/TSA family.
Contains 1 thioredoxin domain.

SWISS:
Q13162

Gene ID:
10549

Database links:

Entrez Gene: 281999 Cow

Entrez Gene: 10549 Human

Entrez Gene: 53381 Mouse

Entrez Gene: 85274 Rat

Omim: 606506 Human

SwissProt: Q9BGI2 Cow

SwissProt: Q13162 Human

SwissProt: O08807 Mouse

SwissProt: Q9Z0V5 Rat

Unigene: 83383 Human

Unigene: 247542 Mouse

Unigene: 17958 Rat



Product Picture
Sample:
K562(Human) Cell Lysate at 30 ug
Primary: Anti-Peroxiredoxin-4 (SL23510R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 27 kD
Observed band size: 27 kD
Sample:
Liver (Mouse) Lysate at 40 ug
Primary: Anti- Peroxiredoxin-4 (SL23510R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 27 kD
Observed band size: 27 kD
Sample:
Hela(Human) Cell Lysate at 30 ug
Primary: Anti-Peroxiredoxin-4  (SL23510R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 27 kD
Observed band size: 27 kD

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