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Product Name EXOC3L2 Chinese Name EXOC3L2蛋白/Hepatitis B Virus X antigen抗体 Alias Exocyst complex component 3 like; Exocyst complex component 3 like protein 2; FLJ36147; EX3L2_HUMAN; HBV X transactivated gene 7 protein; HBV XAg transactivated protein 7; MGC16332; OTTHUMP00000207128; OTTMUSP00000045827; Protein 7 transactivated by hepatitis B virus X antigen (HBxAg); XTP7. Research Area Cell biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species Human, Applications IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 46kDa Cellular localization The nucleus cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human EXOC3L2 : 1-100/409 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Exocytosis is crucial in membrane trafficking and it mediates hormone and neurotransmitter secretion out of the cell, as well as the incorporation of membrane proteins and lipids to the plasma membrane. It is crucial for cell-cell communication, cell growth and cell polarity. The exocyst complex is a multi-protein complex that consists of Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70 and Exo84, and is essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. The exocyst complex inhibits tubulin polymerization in vitro, suggesting that the exocyst complex is important for modulating the microtubule dynamics that underlie exocytosis. ExoC3L2 (Exocyst complex component 3-like protein 2), also known as HBV X-transactivated gene 7 protein, is a 409 amino acid protein that is related to the Sec6 component of the exocyst complex.
Similarity:
Belongs to the SEC6 family.
SWISS:
Q2M3D2
Gene ID:
90332
Database links:Entrez Gene: 90332 Human
SwissProt: Q2M3D2 Human
Product Picture Paraformaldehyde-fixed, paraffin embedded (human brain glioma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (EXOC3L2) Polyclonal Antibody, Unconjugated (SL23507R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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