Product Name	AKAP14
Chinese Name	A激酶锚定蛋白14抗体
Alias	A kinase (PRKA) anchor protein 14; A kinase anchor protein 14; PRKA14; AKAP-14; AKA14_RAT; Protein kinase A-anchoring protein 14; Protein kinase A anchoring protein 14. TAKAP-1.2; Testis-specific A-kinase-anchoring protein TAKAP-80.
Research Area	Signal transduction  Kinases and Phosphatases
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Rat, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	55kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from rat AKAP14: 81-180/502
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of A-kinase anchoring proteins (AKAPs), a family of functionally related proteins that target protein kinase A to discrete locations within the cell. The human ortholog of this gene has been characterized. It is reported to be enriched in airway cilia and to regulate ciliary beat frequency by anchoring the protein kinase A holoenzyme near substrates in the axoneme. [provided by RefSeq, May 2013]. Function: Binds to type II regulatory subunits of protein kinase A and anchors/targets them. Subunit: Binds to type II regulatory subunits (RII). Subcellular Location: Cytoplasm. Tissue Specificity: Present in cilia (at protein level). Expressed in tissues containing axoneme-based organelles (cilia and/or flagella): trachea and testis. Highly expressed in airway cilia. SWISS: O35817 Gene ID: 60332 Database links: Entrez Gene: 434756 Mouse Entrez Gene: 60332 Rat SwissProt: O35817 Rat Unigene: 471848 Mouse Unigene: 42933 Rat
Product Picture	Sample: Testis (Mouse) Lysate at 40 ug Primary: Anti-AKAP14 (SL23424R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55 kD Observed band size: 55 kD

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