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Product Name ATPase Na+/ K+ beta 2 Chinese Name 钠钾ATP酶Channel protein抗体 Alias adhesion molecule on glia; Na+K+ATPase; AMOG; AT1B2; AT1B2_HUMAN; ATP1B2; ATPase Na+/K+ transporting beta 2 polypeptide; ATPB2; ATPB2S; MGC93648; Na+/K+ -ATPase beta 2 subunit; Na, K ATPase beta 2 polypeptide; RATATPB2S; sodium potassium ATPase subunit beta 2 (non-catalytic); sodium pump subunit beta 2; sodium/potassium dependent ATPase beta 2 subunit; Sodium/potassium dependent ATPase subunit beta 2; sodium/potassium transporting ATPase beta 2 chain; sodium/potassium transporting ATPase subunit beta 2; Sodium/potassium-dependent ATPase subunit beta-2; Sodium/potassium-transporting ATPase subunit beta-2. Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, Rat, (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 33kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ATPase Na+/ K+ beta 2: 21-120/290 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 2 subunit. [provided by RefSeq, Jul 2008]
Function:
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known.
Subunit:
Composed of three subunits: alpha (catalytic), beta and gamma.
Subcellular Location:
Membrane; Single-pass type II membrane protein.
Similarity:
Belongs to the X(+)/potassium ATPases subunit beta family.
SWISS:
P14415
Gene ID:
482
Database links:
Entrez Gene: 482 Human
Entrez Gene: 11932 Mouse
Omim: 182331 Human
SwissProt: P14415 Human
SwissProt: P14231 Mouse
Unigene: 643540 Human
Unigene: 235204 Mouse
Unigene: 10624 Rat
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