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Rabbit Anti-CYPIIJ2 antibody
Rabbit Anti-CYPIIJ2 antibody
Arachidonic acid epoxygenase; CP2J2_HUMAN; CPJ2; CYP2J2; Cyp2-j2; Cytochrome P450 2J2; Cytochrome P450 family 2 subfamily J polypeptide 2; Cytochrome P450 subfamily IIJ (arachidonic acid epoxygenase) polypeptide 2; Cytochrome P450 subfamily IIJ polypepti
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Details

Product Name CYPIIJ2
Chinese Name 细胞色素P450ⅡJ2抗体
Alias Arachidonic acid epoxygenase; CP2J2_HUMAN; CPJ2; CYP2J2; Cyp2-j2; Cytochrome P450 2J2; Cytochrome P450 family 2 subfamily J polypeptide 2; Cytochrome P450 subfamily IIJ (arachidonic acid epoxygenase) polypeptide 2; Cytochrome P450 subfamily IIJ polypeptide 2; Flavoprotein linked monooxygenase; Microsomal monooxygenase;   
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 58kDa
Cellular localization cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human CYPIIJ2: 401-501/501 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for epoxidation of endogenous arachidonic acid in cardiac tissue. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jan 2016].

Function:
This enzyme metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools.

Subcellular Location:
Endoplasmic reticulum membrane. Microsome membrane.

Tissue Specificity:
Highly expressed in heart, present at lower levels in liver, ileum, jejunum, colon, and kidney

Similarity:
Belongs to the cytochrome P450 family.

SWISS:
P51589

Gene ID:
1573

Database links:

Entrez Gene: 1573 Human

Omim: 601258 Human

SwissProt: P51589 Human

Unigene: 152096 Human



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