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Product Name Ly-6G Chinese Name lymphocyte抗原6G抗体 Alias Gr-1; Gr1; Ly 6G; Ly-6G.1; Ly6G; lymphocyte antigen 6 complex locus G; Lymphocyte antigen 6G; LY6G_MOUSE. literatures Specific References (1) | SL23111R has been referenced in 1 publications.[IF=3.269] Meihua Ji. et al. Oxycodone protects cardiac microvascular endothelial cells against ischemia/reperfusion injury by binding to Sigma-1 Receptor. BIOENGINEERED. Bioengineered. 2022;13(4):9628-9644 IF ; Rat.Research Area Cell biology immunology Cell Surface Molecule lymphocyte Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, Applications ELISA=1:5000-10000 Flow-Cyt=2ug/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 14kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from mouse Ly-6G: 4-50/134 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Ly6G is a GPI-anchored protein, that is also known as the myeloid differentiation antigen Gr1. The antigen is transiently expressed on monocytes in the bone marrow. The level of antigen expression in the bone marrow directly correlates with granulocyte differentiation and maturation. Ly6G is expressed predominantly on neutrophils, also in a subset of eosinophils, differentiating pre-monocytes, and plasmacytoid dendritic cells.
Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor (By similarity).
Tissue Specificity:
Expressed in bone marrow.
Similarity:
Contains 1 UPAR/Ly6 domain.
SWISS:
P35461
Gene ID:
546644
Database links:Entrez Gene: 546644 Mouse
SwissProt: P35461 Mouse
Ly6G属于是Ly-6家族成员,主要表达于T细胞、单核细胞,中性白细胞等,在抑制抗Tumour和T细胞的应答方面起着重要作用。只要定位于The cell membrane、cytoplasmic。Product Picture Blank control: sp2/0.
Primary Antibody (green line): Rabbit Anti-Ly-6G antibody (SL23111R)
Dilution: 2ug/Test;
Secondary Antibody : Goat anti-rabbit IgG-FITC
Dilution: 0.5ug/Test.
Protocol
The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.
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