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Product Name IL13RA2 Chinese Name 白细胞介素13受体a2抗体 Alias Interleukin-13 receptor subunit alpha-2; IL-13 receptor subunit alpha-2; IL-13 receptor subunit alpha-2; subunit alpha-2; IL-13R-alpha-2; IL-13RA2; CD213a2; IL13R; IL-13R; IL13 receptor; IL13BP; Interleukin 13 binding protein; Interleukin-13-binding protein; I13R2_HUMAN. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, ) Applications WB=1:500-2000 IHC-P=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 41kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from mouse IL-13Ra2 : 21-120/383 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This protein is closely related to IL13RA1, a subunit of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13.
Function:
Binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4).
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Similarity:
Belongs to the type I cytokine receptor family. Type 5 subfamily.
SWISS:
O88786
Gene ID:
16165
Database links:Entrez Gene: 3598 Human
Omim: 300130 Human
SwissProt: Q14627 Human
Unigene: 336046 Human
Product Picture Sample:
Lane 1: Human U251 cell lysates
Lane 2: Human HeLa cell lysates
Primary: Anti-IL13RA2 (SL22785R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 41 kDa
Observed band size: 46 kDa
Paraformaldehyde-fixed, paraffin embedded (human colon carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (IL-13Ra2) Polyclonal Antibody, Unconjugated (SL22785R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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