Product Name	Peroxiredoxin-5
Chinese Name	过氧化还原酶5抗体
Alias	Alu corepressor 1;Antioxidant enzyme B166;AOEB166;Liver tissue 2D-page spot 71B;PLP;Peroxiredoxin V; Prx-V;Peroxisomal antioxidant enzyme;TPx type VI;Thioredoxin peroxidase PMP20;PRDX5;PRDX5_HUMAN
Research Area	Tumour  Cell biology  immunology  Apoptosis  Mitochondrion  Interferon
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Rat,  (predicted: Human, Mouse, Dog, Pig, Cow, Horse, )
Applications	IHC-P=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	22kDa
Cellular localization	cytoplasmic Mitochondrion
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Peroxiredoxin-5: 51-150/214
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein interacts with peroxisome receptor 1 and plays an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. The use of alternate transcription start sites is thought to result in transcript variants that use different in-frame translational start codons to generate isoforms that are targeted to the mitochondrion (isoform L) or peroxisome/cytoplasm (isoform S). Multiple related pseudogenes have been defined for this gene. [provided by RefSeq, Nov 2017] Function: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Subunit: Monomer. Subcellular Location: Mitochondrion. Cytoplasm. Peroxisome. Tissue Specificity: Widely expressed. Similarity: Belongs to the peroxiredoxin 2 family. Contains 1 thioredoxin domain. SWISS: P30044 Gene ID: 25824 Database links: Entrez Gene: 25824 Human Entrez Gene: 54683 Mouse Entrez Gene: 113898 Rat Omim: 606583 Human SwissProt: P30044 Human SwissProt: P99029 Mouse SwissProt: Q9R063 Rat Unigene: 502823 Human Unigene: 279782 Mouse Unigene: 2944 Rat
Product Picture	Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Peroxiredoxin-5) Polyclonal Antibody, Unconjugated (SL22754R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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