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Rabbit Anti-FAM115C antibody
Rabbit Anti-FAM115C antibody
TCAF2_HUMAN; FAM115C; FAM139A; Family with sequence similarity 115, member C; Family with sequence similarity 139 member A; FLJ40722; Protein FAM115C; Protein FAM139A
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Details

Product Name FAM115C
Chinese Name FAM115C蛋白抗体
Alias TCAF2_HUMAN; FAM115C; FAM139A; Family with sequence similarity 115, member C; Family with sequence similarity 139 member A; FLJ40722; Protein FAM115C; Protein FAM139A  
Research Area Cell biology  immunology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human,  (predicted: Mouse, Rat, Dog, Horse, )
Applications WB=1:500-2000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 84kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human FAM115C: 591-690/919 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail TCAF2 (TRPM8 Channel Associated Factor 2) is a Protein Coding gene. Diseases associated with TCAF2 include Retinitis Pigmentosa 11. Gene Ontology (GO) annotations related to this gene include ion channel binding. An important paralog of this gene is TCAF2C.

Function:
Isoform 2: Negatively regulates the plasma membrane cation channel TRPM8 activity. Involved in the recruitment of TRPM8 to the cell surface. Promotes prostate cancer cell migration stimulation in a TRPM8-dependent manner.

Subcellular Location:
Plasma membrane

Similarity:
Belongs to the FAM115 family.

SWISS:
A6NFQ2

Gene ID:
285966

Database links:

Entrez Gene: 285966 Human

SwissProt: A6NFQ2 Human

Unigene: 729402 Human



Product Picture
Sample:
U87MG (Human) Cell Lysate at 30 ug
Huvec (Human) Cell Lysate at 30 ug
A431(Human) Cell Lysate at 30 ug
Primary: Anti-FAM115C (SL22511R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 101/92 kD
Observed band size: 98 kD

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