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Rabbit Anti-HBZ antibody
Rabbit Anti-HBZ antibody
HBAZ; HBAZ_HUMAN; HBZ 2; HBZ2; Hemoglobin subunit zeta; Hemoglobin zeta; Hemoglobin zeta chain; Zeta globin; Zeta-globin.
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Details

Product Name HBZ
Chinese Name 血红蛋白ζ链/Hemoglobin ζ 抗体
Alias HBAZ; HBAZ_HUMAN; HBZ 2; HBZ2; Hemoglobin subunit zeta; Hemoglobin zeta; Hemoglobin zeta chain; Zeta globin; Zeta-globin.  
Research Area Cardiovascular  immunology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, 
Applications WB=1:500-2000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 16kDa
Cellular localization cytoplasmic Extracellular matrix Secretory protein 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human HBZ: 1-100/142 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Zeta-globin is an alpha-like hemoglobin. The zeta-globin polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult life. The zeta-globin gene is a member of the human alpha-globin gene cluster that includes five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 -alpha-1 - theta1 - 3'. [provided by RefSeq, Nov 2009].

Function:
The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin, synthesized primarily in the yolk sac.

Subunit:
Heterotetramer of two zeta chains and two epsilon chains in early embryonic hemoglobin Gower-1; two zeta chains and two gamma chains in hemoglobin Portland-1.

Tissue Specificity:
Red blood cells.

Similarity:
Belongs to the globin family

SWISS:
P02008

Gene ID:
3050

Database links:

Entrez Gene: 3050 Human

Omim: 142310 Human

SwissProt: P02008 Human

Unigene: 585357 Human



Product Picture
Sample:
K562(Human) Cell Lysate at 30 ug
K562(Human) Cell Lysate at 30 ug
Primary: Anti-HBZ (SL22473R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 16/35 kD
Observed band size: 35 kD

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