Product Name	GLUT3
Chinese Name	葡萄糖Transporter3抗体
Alias	facilitated glucose transporter member 3; Glucose Transporter GLUT3 ; FLJ90380; Glucose Transporter Type 3; Glucose transporter type 3 brain; GLUT 3; GLUT-3; GTR3_HUMAN; SLC2A3; Solute Carrier Family 2 (Facilitated Glucose Transporter) Member 3; Solute carrier family 2.
Research Area	Tumour  Cell biology  Signal transduction  The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse,  (predicted: Rat, )
Applications	WB=1:500-2000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	54kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse GLUT3 : 431-496/496 <Cytoplasmic>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	may act as a glucose transporter in neurons; may mediate increasd glucose uptake in response to neuronal injury. Glucose is fundamental to the metabolism of mammalian cells. Several glucose transporter protein (Glut) isoforms have been identified and shown to function in response to insulin and IGF1 induced signaling. GLUT3 is detectable in a few normal cell type spermatids in testis with active spermatogenesis, placental trophoblast membranes, and neurons in brain. GLUT3 staining is also detectable in human cancers including those of the ovary, lung, and testis. Alternative names: FLJ90380; Glucose Transporter Type 3; Glucose transporter type 3 brain; GLUT 3; GLUT3; SLC2A3; Solute Carrier Family 2 (Facilitated Glucose Transporter) Member 3. Function: Facilitative glucose transporter. Probably a neuronal glucose transporter. Subcellular Location: Cell membrane; Multi-pass membrane protein. Melanosome. Tissue Specificity: Highly expressed in brain. Expressed in many tissues. Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. SWISS: P11169 Gene ID: 6515 Database links: Entrez Gene: 6515 Human Entrez Gene: 20527 Mouse Entrez Gene: 25551 Rat Omim: 138170 Human SwissProt: P11169 Human SwissProt: P32037 Mouse SwissProt: Q07647 Rat Unigene: 419240 Human Unigene: 395108 Mouse Unigene: 95055 Rat 交换和转运（Trafficking and Transport） GLUT-3属于溶质运载蛋白家族成员（solute carrier family），主要功能是转载葡萄糖进入epithelial cells。 目前主要用于Diabetes肾病和视网膜病变的研究，也是肾小球系膜细胞上的主要葡萄糖转运体。GLUT3的功能状态直接影响系膜细胞的糖代谢及功能变化。 近期，研究人员也用来区别一些良、恶性Tumour的鉴别。
Product Picture	Sample: HepG2(Human) Cell Lysate at 30 ug SH-SY5Y(Human) Cell Lysate at 30 ug NIH/3T3(Mouse) Cell Lysate at 30 ug Raw264.7(Mouse) Cell Lysate at 30 ug Primary: Anti-GLUT3 (SL22375R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 54/60 kD Observed band size: 60 kD

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