Product Name	CTGF
Chinese Name	结缔组织生长因子抗体
Alias	CCN 2; CCN-2; CCN2; Connective Tissue Growth Factor; CTGF; Hcs 24; Hcs24; Hypertrophic chondrocyte specific protein 24; Hypertrophic chondrocyte-specific gene product 24; Insulin-like Growth Factor-Binding Protein 8; MGC102839; NOV 2; NOV2; Connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP8; IGFBP-8; connective tissue growth factor precursor; CTGF_HUMAN.
literatures	Specific References  (1)     |     SL22361R has been referenced in 1 publications. [IF=4.23] Zhu, Boqian. et al. Protective effect of rosuvastatin against the formation of benign esophageal stricture. 2021 Nov 20  IHC ;  Rabbit.   PubMed:34800196
Research Area	Cardiovascular  immunology  Growth factors and hormones
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Rabbit, )
Applications	WB=1:500-2000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	36kDa
Cellular localization	Extracellular matrix Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CTGF: 27-120/349
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009]. Function: Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Subunit: Monomer. Subcellular Location: Secreted, extracellular space, extracellular matrix. Secreted. Tissue Specificity: Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested. Similarity: Belongs to the CCN family. Contains 1 CTCK (C-terminal cystine knot-like) domain. Contains 1 IGFBP N-terminal domain. Contains 1 TSP type-1 domain. Contains 1 VWFC domain. SWISS: P29279 Gene ID: 1490 Database links: Entrez Gene: 1490 Human Entrez Gene: 64032 Rat Omim: 121009 Human SwissProt: P29279 Human SwissProt: P29268 Mouse SwissProt: Q9R1E9 Rat Unigene: 410037 Human Unigene: 390287 Mouse Growth factors and hormones（ Growth Factor and Hormones） 结缔组织生长因子（CTGF）是调节细胞增生、分化和Extracellular matrix形成的重要效应分子,可调节机体有关组织、细胞生长并与纤维化发生密切相关的一种因子，因而在肌体的各类创伤修复过程中具有重要的生理学意义。
Product Picture	Sample: U251(Human) Cell Lysate at 30 ug Kidney(Mouse) Lysate at 40 ug Kidney(Rat) Lysate at 40 ug Primary: Anti-CTGF (SL22361R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 38/35 kD Observed band size: 38/35 kD

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