Product Name	Brucella
Chinese Name	布氏杆菌抗体
Alias	Brucella bacterial;   布鲁氏菌; 布鲁氏杆菌; 布鲁氏杆菌病; 布鲁氏病; 布鲁氏病菌; 布氏杆菌菌体蛋白; 布病;
literatures	Specific References  (12)     |     SL2229R has been referenced in 12 publications. [IF=13.751] Fengguang Guo. et al. Live attenuated bacterium limits cancer resistance to CAR-T therapy by remodeling the tumor microenvironment. J Immunother Cancer. 2022 Jan;10(1):e003760  IF ;  Mouse.   PubMed:34987022 [IF=8.786] Stranahan Lauren W.. et al. Primary and memory immune responses against rough Brucella canis are less robust compared to smooth B. abortus and B. melitensis following intratracheal infection in mice. FRONT IMMUNOL. 2022 Aug;0:4494  IHC ;  Mouse.   PubMed:36032120 [IF=8.146] Kelsey Michelle Wells. et al. Brucella activates the host RIDD pathway to subvert BLOS1-directed immune defense. ELIFE. 2022; 11: e73625  IF ;  null,Mouse.   PubMed:35587649 [IF=6.064] Martha E. Hensel. et al. Intratracheal inoculation results in Brucella-associated reproductive disease in male mouse and guinea pig models of infection.. FRONT MICROBIOL. 2022 Oct;13:1029199-1029199  IHC ;  Mouse, Guinea pig.   PubMed:36338077 [IF=5.77] Charles R. Moley. et al. Innate Lymphoid Cells and Interferons Limit Neurologic and Articular Complications of Brucellosis. AM J PATHOL. 2023 May;:  IHC ;  Mouse.   PubMed:37263343 [IF=4.282] Hensel ME et al. Vaccine Candidate Brucella melitensis 16MΔvjbR Is Safe in a Pregnant Sheep Model and Confers Protection. mSphere. 2020 May 13;5(3):e00120-20.  IHC-P ;  Sheep.   PubMed:32404509 [IF=3.256] Khalaf OH et al. The NOD-scid IL2rγnull Mouse Model Is Suitable for the Study of Osteoarticular Brucellosis and Vaccine Safety. Infect Immun. 2019 May 21;87(6). pii: e00901-18.  IHC-P&IHF ;  Mouse.   PubMed:30936160 [IF=3.201] Martha E. Hensel. et al. Intratracheal Inoculation with Brucella melitensis in the Pregnant Guinea Pig Is an Improved Model for Reproductive Pathogenesis and Vaccine Studies. Infect Immun. 2020 Sep;88(10):e00204-20  IHC ;  Pig.   PubMed:32690632 [IF=3.143] Raquel M et al. Evaluation of the safety profile of the vaccine candidate Brucella melitensis 16MΔvjbR strain in GoatsVaccine.2021 Jan 15;39(3):617-625.  IHC ;  Goat.   PubMed:33328142 [IF=2.776] Stranahan LW et al. Characterization of Brucella canis infection in mice. PLoS One. 2019 Jun 20;14(6):e0218809.  IHC-P&iELISA ;  Mouse.   PubMed:31220185 [IF=2.495] Xin Hu. et al. The role of CXCR3 and its ligands expression in Brucellar spondylitis. Bmc Immunol. 2020 Dec;21(1):1-8  IHC ;  Human.   PubMed:33208100 [IF=2.02] Wareth, Gamal, et al. "Experimental infection of chicken embryos with recently described Brucella microti: Pathogenicity and pathological findings."Comparative Immunology, Microbiology and Infectious Diseases (2015).  IHC-P ;  Chicken.   PubMed:26264524
Research Area	Microbiology
Immunogen Species	Rabbit
Clonality	Polyclonal
Applications	ELISA=1:1000-5000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	N/AkDa
Form	Liquid
Concentration	1mg/ml
immunogen	whole cell protein of Brucella
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Brucella species are small, Gram-negative, facultative coccobacilli, most lacking a capsule, endospores, or native plasmids. They are intracellular within the host organism, and show environmental persistence outside the host. They survive extremes in temperature, pH, and humidity, and in frozen and aborted materials. They infect many species, but with some specificity. SWISS: N/A Gene ID: N/A 布氏杆菌属（Brucella）是一类革兰氏阴性的短小杆菌，牛、羊、猪等动物最易感染，引起母畜传染性流产。人类接触带菌动物或食用病畜及其乳制品，均可被感染。布氏杆菌病广泛分布世界各地。我国部分地区曾有流行，现已基本控制。布氏杆菌也是帝国主义者列为失能性生物战剂之一。布氏杆菌属分为羊、牛、猪、鼠、绵羊及犬布氏杆菌6个种，20个生物型。中国流行的主要是羊（Br.melitensis）、牛(Br.Bovis)、猪(Br.suis)三种布氏杆菌，其中以羊布氏杆菌病最为多见. 布氏杆菌首先感染家畜。家畜临床表现不明显。但怀孕的母畜则极易引起流产或死胎，所排出的羊水、胎盘、分泌物中含大量布氏杆菌，特别有传染力。而其皮毛，尿粪，奶液中均有此菌。排菌可长达三个月以上。 人通过与家畜的接触，服用了污染的奶及畜肉，吸入了含菌的尘土或菌进入眼结合膜等途径，皆可遭受感染。发病年龄大多在30岁以上。 该菌自损伤的皮肤及粘膜或消化道，呼吸道进入人体后，首先被吞噬细胞吞噬，进入淋巴结，有时可在其中存活并生长繁殖形成感染灶，约2～3周后可进入血液循环产生菌血症。继之在网状内皮系统如肝，脾，骨髓内生长形成新的感染病灶，并可多次反复冲破细胞进入血循中，则再一次引起菌血症和临床急性症状，表现为平均2～3周的发烧期，每间隔约3天至两周，发烧又反复，产生波浪状的热型，故称为波浪热。 布氏杆菌含有内毒素及菌体本身皆可引起人体的过敏，出现各种的变态反应性病变。骨关节病变，多发生在半年左右，少数病例更早些。布氏杆菌骨髓炎是血源性布氏杆菌感染在骨关节的局部表现。任何骨均可受累，但以脊椎炎最为多见。关节的病变常侵犯大关节，以髋关节炎最为常见。慢性病人可伴有其它多处的关节病变。但大多数发生在腰椎，少数发生在胸椎，胸腰段，骶椎或骶髂关节者。男性病人可有睾丸肿大，睾丸炎症表现。
Product Picture	Measured by its binding ability in a indirect ELISA. Immobilized Brucella bacterial protein (Cat. SL2229P) at 2 μg/mL (100 μL/well) can bind   Rabbit Anti-Brucella Antibody, the EC50 is 61.32 ng/mL.

Cartpieces

• 
• 1

  1Delete

• 
• 5

  5Delete

• 
• S

  SDelete

• 
• R

  RDelete

• 
• +

  +Delete

• 
• 4

  4Delete

• Delete

• Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• 
• $

  $Delete

• 
• 0

  0Delete

• 
• 4

  4Delete

• 
• $

  $Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 1

  1Delete

• 
• B

  BDelete

• 
• B

  BDelete

• 

• Delete

• 
• i

  iDelete

• 
• i

  iDelete

• Delete

• 
• 1

  1Delete

• Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• 
• 0

  0Delete

• Delete

• 
• 2

  2Delete

• 
• 1

  1Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• Delete

• 
• -

  -Delete

• 
• -

  -Delete

• 
• 0

  0Delete

• Delete

• 
• t

  tDelete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• f

  fDelete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• 
• 4

  4Delete

• 
• $

  $Delete

• Delete

• 
• 0

  0Delete

• Delete

• Delete

• Delete

• 
• R

  RDelete

• 
• 5

  5Delete

• 
• A

  ADelete

Totalgoods,subtotals:￥Checkout