Product Name	GPX1
Chinese Name	谷胱甘肽过氧化酶1
Alias	Glutathione peroxidase 1; Cellular glutathione peroxidase; GPx 1; GPx-1;GPX1_HUMAN; GSHPx-1; GSHPX1; MGC14399; MGC88245.
literatures	Specific References  (2)     |     SL22273R has been referenced in 2 publications. [IF=4.087]   WB ;  Rat.   PubMed:33300653 [IF=4.087] Zhang Y et al. Gentiopicroside prevents alcoholic liver damage by improving mitochondrial dysfunction in the rat modelPhytother Res.2020 Dec 10.  WB ;  Rat.   PubMed:33300653
Research Area	Tumour  Cardiovascular  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Rat,  (predicted: Human, Mouse, )
Applications	IHC-P=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	22kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse GPX1: 31-130/201
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene product belongs to the family of glutathione peroxidase, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq]. Subunit: Homotetramer. Interacts with MIEN1 (By similarity). Subcellular Location: Cytoplasm. Similarity: Belongs to the glutathione peroxidase family. SWISS: P11352 Gene ID: 14775 Database links: Entrez Gene: 461015 Chimpanzee Entrez Gene: 281209 Cow Entrez Gene: 2876 Human Entrez Gene: 706732 Macaque Monkey Entrez Gene: 14775 Mouse Entrez Gene: 100438450 Orangutan Entrez Gene: 397403 Pig Entrez Gene: 24404 Rat Omim: 138320 Human SwissProt: Q0EFA0 Chimpanzee SwissProt: P00435 Cow SwissProt: P07203 Human SwissProt: Q865R2 Macaque Monkey SwissProt: P11352 Mouse SwissProt: Q4AEI3 Orangutan SwissProt: Q8MJ14 Pig SwissProt: P04041 Rat Unigene: 76686 Human Unigene: 1090 Mouse Unigene: 11323 Rat 保护红细胞中血红蛋白的氧化分解.
Product Picture	Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GPX1) Polyclonal Antibody, Unconjugated (SL22273R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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