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Product Name PGK1 Chinese Name 磷酸激酶1抗体 Alias Cell migration-inducing gene 10 protein; MGC117307; MGC8947; MIG10; pgk1; PGK1_HUMAN; PGKA; Phosphoglycerate kinase 1; Primer recognition protein 2; PRP 2; PRP 2. Research Area Tumour Cell biology immunology Neurobiology Signal transduction Kinases and Phosphatases The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Cow, Horse, Sheep, ) Applications WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 44kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human PGK1: 241-340/417 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. This gene lies on the X-chromosome, while a related pseudogene also has been found on the X-chromosome and another on chromosome 19. [provided by RefSeq]
Function:
In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein).
Subunit:
Monomer.
Subcellular Location:
Cytoplasm.
DISEASE:
Phosphoglycerate kinase 1 deficiency (PGK1D) [MIM:300653]: A condition with a highly variable clinical phenotype that includes hemolytic anemia, rhabdomyolysis, myopathy and neurologic involvement. Patients can express one or more of these manifestations. Note=The disease is caused by mutations affecting the gene represented in this entry.
Similarity:
Belongs to the phosphoglycerate kinase family.
SWISS:
P00558
Gene ID:
5230
Database links:
Entrez Gene: 5230 HumanEntrez Gene: 18655 Mouse
Omim: 311800 Human
SwissProt: P00558 Human
SwissProt: P09411 Mouse
Unigene: 78771 Human
Unigene: 336204 Mouse
Unigene: 336205 Mouse
Unigene: 108127 Rat
Product Picture Sample:
Kidney (Mouse) Lysate at 40 ug
Primary: Anti- PGK1 (SL21868R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 44 kD
Observed band size: 44 kD
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