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Product Name CD7 Chinese Name CD7抗体 Alias CD7; CD7 antigen (p41); CD7 molecule; CD7_HUMAN; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen Leu-9; CD 7; CD7 antigen; CD7 antigen p41; CD7 molecule; GP 40; GP40; LEU 9; LEU9; p41; p41 protein; T cell antigen CD7; T cell antigen CD7 precursor; T cell leukemia antigen; Tp 40; TP 41; Tp40; TP41. literatures Specific References (1) | SL21860R has been referenced in 1 publications.[IF=2.984] Heli Zhang. et al. FN1 promotes chondrocyte differentiation and collagen production via TGF-β/PI3K/Akt pathway in mice with femoral fracture. Gene. 2021 Feb;769:145253 IHC ; Mouse.Research Area Cell biology immunology t-lymphocyte Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, Rat, Applications WB=1:500-2000 IHC-P=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 24kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human CD7 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development. [provided by RefSeq, Jul 2008]
Function:
Not yet known.
Subunit:
Interacts with SECTM1.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Similarity:
Contains 1 Ig-like (immunoglobulin-like) domain.
SWISS:
P50283
Gene ID:
12516
Database links:
Entrez Gene: 924 HumanEntrez Gene: 12516 Mouse
Omim: 186820 Human
SwissProt: P09564 Human
SwissProt: P50283 Mouse
Unigene: 36972 Human
Unigene: 4100 Mouse
CD7是一种40kDa的glycoprotein,为Ig超级基因家族的成员,在绝大多数成熟与不成熟T细胞和T细胞白血病中表达,但也表达于NK细胞、小部分正常B细胞和恶性B细胞。如T细胞其它标记物抗体无效,可用CD7来鉴别原始T细胞Tumour如淋巴母细胞白血病。Product Picture Sample:
Small intestine (Mouse) Lysate at 40 ug
Primary: Anti-CD7 (SL21860R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 24 kD
Observed band size: 24 kD
Paraformaldehyde-fixed, paraffin embedded (rat lymphoid); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CD7) Polyclonal Antibody, Unconjugated (SL21860R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.Paraformaldehyde-fixed, paraffin embedded (rat spleen); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CD7) Polyclonal Antibody, Unconjugated (SL21860R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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