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Rabbit Anti-CD7  antibody
Rabbit Anti-CD7 antibody
CD7; CD7 antigen (p41); CD7 molecule; CD7_HUMAN; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen Leu-9; CD 7; CD7 antigen; CD7 antigen p41; CD7 molecule; GP 40; GP40; LEU 9; LEU9; p41; p41 protein; T cell antigen CD7; T cell antigen CD
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Details

Product Name CD7
Chinese Name CD7抗体
Alias CD7; CD7 antigen (p41); CD7 molecule; CD7_HUMAN; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen Leu-9; CD 7; CD7 antigen; CD7 antigen p41; CD7 molecule; GP 40; GP40; LEU 9; LEU9; p41; p41 protein; T cell antigen CD7; T cell antigen CD7 precursor; T cell leukemia antigen; Tp 40; TP 41; Tp40; TP41.  
literatures
Specific References  (1)     |     SL21860R has been referenced in 1 publications.
[IF=2.984] Heli Zhang. et al. FN1 promotes chondrocyte differentiation and collagen production via TGF-β/PI3K/Akt pathway in mice with femoral fracture. Gene. 2021 Feb;769:145253  IHC ;  Mouse.  
Research Area Cell biology  immunology  t-lymphocyte  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse, Rat, 
Applications WB=1:500-2000 IHC-P=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 24kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human CD7  
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development. [provided by RefSeq, Jul 2008]

Function:
Not yet known.

Subunit:
Interacts with SECTM1.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Similarity:
Contains 1 Ig-like (immunoglobulin-like) domain.

SWISS:
P50283

Gene ID:
12516

Database links:
Entrez Gene: 924 Human

Entrez Gene: 12516 Mouse

Omim: 186820 Human

SwissProt: P09564 Human

SwissProt: P50283 Mouse

Unigene: 36972 Human

Unigene: 4100 Mouse



CD7是一种40kDa的glycoprotein,为Ig超级基因家族的成员,在绝大多数成熟与不成熟T细胞和T细胞白血病中表达,但也表达于NK细胞、小部分正常B细胞和恶性B细胞。如T细胞其它标记物抗体无效,可用CD7来鉴别原始T细胞Tumour如淋巴母细胞白血病。
Product Picture
Sample:
Small intestine (Mouse) Lysate at 40 ug
Primary: Anti-CD7 (SL21860R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 24 kD
Observed band size: 24 kD
Paraformaldehyde-fixed, paraffin embedded (rat lymphoid); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CD7) Polyclonal Antibody, Unconjugated (SL21860R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (rat spleen); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CD7) Polyclonal Antibody, Unconjugated (SL21860R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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