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Product Name SLC1A5 Chinese Name 溶质携带物家族-1抗体 Alias Solute carrier family 1; (glutamate transporter), member 7; R16; AAAT; ATBO; M7V1; RDRC; ASCT2; M7VS1; FLJ31068; Baboon M7 virus receptor; RD114/simian type D retrovirus receptor; Sodium-dependent neutral amino acid transporter type 2; Solute carrier family 1 member 5; Neutral amino acid transporter B(0); ATB(0); RD114/simian type D retrovirus receptor; Sodium-dependent neutral amino acid transporter type 2; AAAT_HUMAN. Research Area Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species Human, Mouse, Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 56kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from mouse Solute carrier family 1: 161-260/541 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail solute carrier family 1 (neutral amino acid transporter), member 5. mediates infections of RD114 feline endogenous virus, baboon endogenous virus and type D simian retroviruses; baboon M7 virus receptor; RD114 virus receptor; neutral amino acid transporter B.
Function:
Has a broad substrate specificity, a preference for zwitterionic amino acids, and a sodium-dependence. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated amino acids, anionic amino acids, and cationic amino acids. Acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses.
Subcellular Location:
Membrane; Multi-pass membrane protein (Probable). Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Tissue Specificity:
Placenta, lung, skeletal muscle, kidney, pancreas, and intestine.
Similarity:
Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A5 subfamily.
SWISS:
P51912
Gene ID:
20514
Database links:
Entrez Gene: 6510 HumanEntrez Gene: 20514 Mouse
Omim: 109190 Human
SwissProt: Q15758 Human
SwissProt: P51912 Mouse
Unigene: 631582 Human
Unigene: 1056 Mouse
Product Picture Sample:
RAW264.7 (Mouse) Cell Lysate at 30 ug
Placenta (Mouse) Lysate at 40 ug
Lung (Mouse) Lysate at 40 ug
Cerebrum (Mouse) Lysate at 40 ug
Primary: Anti-Solute carrier family 1 (SL21518R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 56 kD
Observed band size: 56 kD
Sample:
Lymph node (Mouse) Lysate at 40 ug
Primary: Anti- Solute carrier family 1 (SL21518R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 56 kD
Observed band size: 53 kD
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