Product Name	Nkx2.5
Chinese Name	心脏特异性同源盒转录因子NKX2.5抗体
Alias	Cardiac-specific homeobox 1; Cardiac-specific homeobox 1; Cardiac-specific homeobox; CHNG5; CSX; CSX1; Homeobox protein CSX; Homeobox protein NK-2 homolog E; NK2 transcription factor related, locus 5 (Drosophila); Nkx2-5; NKX2.5; Nkx2E; NKX4-1; Tinman paralog.
Research Area	Cardiovascular  Cell biology  Developmental biology  Neurobiology  Stem cells  transcriptional regulatory factor
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	36kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse Nkx2.5
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	In humans, mutations of the gene encoding the homeobox transcription factor Nkx2.5 result in electrical conduction defects and morphological abnormalities of the heart (Dupays et al., 2005). In the heart, Nkx2.5 is expressed in both the myocardium and the endocardium. Differentiation of embryonic stem cells to Nkx2.5-positive cardiomyocytes is facilitated by Wnt11. Subcellular Location: Nuclear SWISS: P42582 Gene ID: 1482 Database links: Entrez Gene: 1482 Human Entrez Gene: 18091 Mouse Entrez Gene: 114109 Rat Omim: 600584 Human SwissProt: Q90788 Chicken SwissProt: P52952 Human SwissProt: P42582 Mouse SwissProt: O35767 Rat Unigene: 638 Chicken Unigene: 54473 Human Unigene: 41974 Mouse Unigene: 6179 Rat
Product Picture	Sample: U-2OS (Human) Cell Lysate at 30 ug Primary: Anti-Nkx2.5 (SL21479R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 36 kD Observed band size: 36 kD

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