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Product Name LCN12 Chinese Name 附睾特异蛋白12抗体 Alias Epididymal-specific lipocalin-12; LCN12; LCN12_MOUSE; Lipocalcin 12; Lipocalin 12; MGC34753; MGC48935. Research Area Cell biology Signal transduction t-lymphocyte Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Mouse, Rat, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 19kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from mouse LCN12: 51-150/193 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Members of the lipocalin family, such as LCN12, have a common structure consisting of an 8-stranded antiparallel beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic ligands and transport them to specific cells (Suzuki et al., 2004 [PubMed 15363845]).[supplied by OMIM, Aug 2009]
Function:
Binds all-trans retinoic acid and may act as a retinoid carrier protein within the epididymis. May play a role in male fertility.
Subcellular Location:
Secreted.
Similarity:
Belongs to the calycin superfamily. Lipocalin family.
SWISS:
Q6JVL5
Gene ID:
77701
Database links:
Entrez Gene: 286256 Human
Entrez Gene: 77701 Mouse
Omim: 612905 Human
SwissProt: Q6JVE5 Human
SwissProt: Q6JVL5 Mouse
Unigene: 440519 Human
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