Product Name	CNGA2
Chinese Name	环核苷酸阳离子Channel proteinα2抗体
Alias	CNCA; CNCA1; CNG2; FLJ46312; OCNC1; OCNCa; OCNCALPHA; olfactory cyclic nucleotide-gated ion channel alpha subunit; olfactory ion channel protein; Cyclic nucleotide-gated olfactory channel; Cyclic nucleotide-gated cation channel 2; Cyclic nucleotide-gated channel alpha-2; CNG channel alpha-2; CNG-2; Cyclic nucleotide-gated olfactory channel subunit OCNC1; CNGA2_HUMAN.
literatures	Specific References  (2)     |     SL2074R has been referenced in 2 publications. [IF=7.571] Rui Zhang. et al. Multifunctional silicon calcium phosphate composite scaffolds promote stem cell recruitment and bone regeneration. J MATER CHEM B. 2022 Jun;:  IHC ;  Rat.   PubMed:35737023 [IF=4.85] Hongxiang Mei. et al. Enhanced PDGFR/Wnt/β-catenin activity of mesenchymal stem cells with high migration ability rescue bone loss of osteoporosis. CELL SIGNAL. 2022 Jun;:110394  IHC ;  Rat.   PubMed:35753532
Research Area	Cardiovascular  Neurobiology  Channel protein
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	73kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CNGA2: 155-250/664 <Cytoplasmic>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. CNGA2 belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family and contains one cyclic nucleotide-binding domain. It may be involved in odorant signal transduction. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons. Function: Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons. Subcellular Location: Membrane; Multi-pass membrane protein. Similarity: Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA2 subfamily. Contains 1 cyclic nucleotide-binding domain. SWISS: Q16280 Gene ID: 1260 Database links: Entrez Gene: 1260 Human Entrez Gene: 12789 Mouse Entrez Gene: 25411 Rat Omim: 300338 Human SwissProt: Q16280 Human SwissProt: Q62398 Mouse SwissProt: Q00195 Rat Unigene: 447360 Human Unigene: 5097 Mouse Unigene: 10384 Rat 环核苷酸阳离子Channel proteinα2为阳离子通道结构蛋白。

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