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Product Name IL-22 Chinese Name 白介素-22抗体 Alias Interleukin-22; Il22; Iltif; ILTIFa; MGC129416; MGC129417; IL-10-related T-cell-derived-inducible factor; IL-TIF; ILTIF; IL-TIF alpha; Interleukin-22a; IL-22a; IL 21; IL D110; IL TIF; IL21; IL22; ILD110; interleukin 21; MGC79382; MGC79384; TIFa; TIFIL 23; TIFIL-23; TIFIL23; zcyto18; Cytokine Zcyto18. literatures Specific References (1) | SL20683R has been referenced in 1 publications.[IF=5.307] Xu Zhou. et al. Magnesium isoglycyrrhizinate ameliorates lipopolysaccharide-induced liver injury by upregulating autophagy and inhibiting inflammation via IL-22 expression. BIOORG CHEM. 2022 Nov;128:106034 IHC, WB ; Mouse.Research Area immunology Growth factors and hormones Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, Dog, Horse, ) Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 17kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human IL-22: 81-150/179 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells. The encoded protein is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed phenotype of T cells after infection by herpesvirus samimiri. [provided by RefSeq].
Function:
Cytokine that contributes to the inflammatory response in vivo.
Subcellular Location:
Secreted.
Similarity:
Belongs to the IL-10 family.
SWISS:
Q9GZX6
Gene ID:
50616
Database links:Entrez Gene: 50616 Human
Entrez Gene: 50929 Mouse
Omim: 605330 Human
SwissProt: Q9GZX6 Human
SwissProt: Q9JJY9 Mouse
Unigene: 287369 Human
Unigene: 103585 Mouse
Unigene: 195879 Rat
IL-22是白介素-10家族的成员,主要是由激活的T lymphocyte产生的一类重要的cell factor,除了在Th17细胞中高表达之外,在NK和NKT等细胞中也有表达,在组织损伤修复以及牛皮癣、肝炎、肺炎、肠炎等慢性炎症中发挥重要作用.IL-22是继IL-6和IL-10之后又一个参与炎症反应和代谢调控的cell factor,IL-22有可能成为干预脂肪肝发生发展的新方法。
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