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Rabbit Anti-phospho-DNPEP (Ser109)antibody
Rabbit Anti-phospho-DNPEP (Ser109)antibody
DNPEP(phospho S109); DNPEP(phospho Ser109); Aspartyl aminopeptidase; ASPEP; DAP; DNPEP_HUMAN.
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  • NO.:SL20424R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Sheep,)
    Applications:IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Product Name phospho-DNPEP (Ser109)
Chinese Name 磷酸化天冬氨酰氨基肽酶(S109)抗体
Alias DNPEP(phospho S109); DNPEP(phospho Ser109); Aspartyl aminopeptidase; ASPEP; DAP; DNPEP_HUMAN.  
literatures
Specific References  (1)     |     SL20424R has been referenced in 1 publications.
[IF=4.982] Geng N et al. A PAK5‐DNPEP‐USP4 axis dictates breast cancer growth and metastasis. Int J Cancer. 2019 Jun 20.  IHC-P,IP,WB& GST pull-down ;  Human&Mouse.  
Product Type Phosphorylated anti 
Research Area Signal transduction  Channel protein  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Sheep, )
Applications IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 52kDa
Cellular localization cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthesised phosphopeptide derived from human DNPEP around the phosphorylation site of Ser109: RR(p-S)QV 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail The protein encoded by this gene is an aminopeptidase which prefers acidic amino acids, and specifically favors aspartic acid over glutamic acid. It is thought to be a cytosolic protein involved in general metabolism of intracellular proteins. [provided by RefSeq, Jul 2008]

Function:
Aminopeptidase with specificity towards an acidic amino acid at the N-terminus. Likely to play an important role in intracellular protein and peptide metabolism.

Subunit:
Tetrahedron-shaped homododecamer built from six homodimers.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Ubiquitous.

DISEASE:
Belongs to the peptidase M18 family.

SWISS:
Q9ULA0

Gene ID:
23549

Database links:

Entrez Gene: 23549 Human

Entrez Gene: 13437 Mouse

Entrez Gene: 301529 Rat

Omim: 611367 Human

SwissProt: Q9ULA0 Human

SwissProt: Q9Z2W0 Mouse

Unigene: 258551 Human

Unigene: 24680 Mouse

Unigene: 65448 Rat



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