Product Name	DHX38
Chinese Name	DHX38蛋白抗体
Alias	ATP dependent RNA helicase DHX38; ATP-dependent RNA helicase DHX38; DDX38; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 38; DEAH (Asp-Glu-Ala-His) box polypeptide 38; DEAH box protein 38; DHX38; KIAA0224; Pre mRNA splicing factor ATP dependent RNA helicase PRP16; Pre-mRNA splicing factor 16; Pre-mRNA-splicing factor ATP-dependent RNA helicase prp16; Prp16; PRP16 homolog of S.cerevisiae; pre-mRNA splicing factor ATP-dependent RNA helicase PRP16; PRP16_HUMAN; PRPF16.
literatures	Specific References  (1)     |     SL20309R has been referenced in 1 publications. [IF=5.722] Zou, Xiaopan. et al. ZMIZ2 promotes the development of triple-receptor negative breast cancer. Cancer Cell Int. 2022 Dec;22(1):1-16  WB ;  Human.   PubMed:35101047
Research Area	Cell biology  Developmental biology  Cell differentiation  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Cow, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	140kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DHX38: 201-300/1277
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a member of the DEAD/H box family of splicing factors. This protein resembles yeast Prp16 more closely than other DEAD/H family members. It is an ATPase and essential for the catalytic step II in pre-mRNA splicing process. [provided by RefSeq, Jul 2008] Function: Probable ATP-binding RNA helicase involved in pre-mRNA splicing. Subcellular Location: Nucleus. Similarity: Belongs to the DEAD box helicase family. DEAH subfamily. PRP16 sub-subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. SWISS: Q92620 Gene ID: 9785 Database links: Entrez Gene: 9785 Human Entrez Gene: 64340 Mouse Entrez Gene: 292007 Rat GenBank: NM_014003 Human Omim: 605584 Human SwissProt: Q17R09 Cow SwissProt: Q92620 Human Unigene: 151218 Human Unigene: 23705 Mouse Unigene: 108087 Rat

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