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Rabbit Anti-CSGLCAT antibody
Rabbit Anti-CSGLCAT antibody
Chondroitin sulfate glucuronyltransferase; Chondroitin synthase 3; CSGlcA-T; ChSy 3; ChSy-3; CHPF2; ChPF-2; CSGLCA T; N acetylgalactosaminyl proteoglycan 3 beta glucuronosyltransferase; CHPF2_HUMAN; Chondroitin polymerizing factor 2; Chondroitin sulfate g
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  • NO.:SL20304R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Chicken,Pig,Cow,Horse,Rabbit,Sheep,)
    Applications:ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name CSGLCAT
Chinese Name 硫酸软骨素聚合酶3抗体
Alias Chondroitin sulfate glucuronyltransferase; Chondroitin synthase 3; CSGlcA-T; ChSy 3; ChSy-3; CHPF2; ChPF-2; CSGLCA T; N acetylgalactosaminyl proteoglycan 3 beta glucuronosyltransferase; CHPF2_HUMAN; Chondroitin polymerizing factor 2; Chondroitin sulfate glucuronyltransferase; N acetylgalactosaminyl proteoglycan 3 beta glucuronosyltransferase; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase.  
Research Area Cell biology  glycoprotein  Cell type markers  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 86kDa
Cellular localization cytoplasmic The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human CSGLCAT: 21-120/772 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail CSGlcA-T is a 772 amino acid single-pass type II membrane protein of the golgi apparatus that belongs to the chondroitin N-acetylgalactosaminyltransferase family. Widely expressed and existing as two alternatively spliced isoforms, CSGlcA-T is found at highest levels in small intestine, pancreas and placenta, with lower levels in heart, brain, kidney, and skeletal muscle where it transfers glucuronic acid from UDP-glucuronic acid to N-acetylgalactosamine residues of elongating chondroitin polymers. The gene encoding CSGlcA-T maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome and Lissencephaly.

Function:
Transfers glucuronic acid (GlcUA) from UDP-GlcUA to N-acetylgalactosamine residues on the non-reducing end of the elongating chondroitin polymer. Has no N-acetylgalactosaminyltransferase activity.

Subcellular Location:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein (Probable).

Tissue Specificity:
Ubiquitous. Highly expressed in placenta, small intestine and pancreas.

Similarity:
Belongs to the chondroitin N-acetylgalactosaminyltransferase family

SWISS:
Q9P2E5

Gene ID:
54480

Database links:

Entrez Gene: 54480 Human

Entrez Gene: 100910 Mouse

Entrez Gene: 296733 Rat

Omim: 608037 Human

SwissProt: Q9P2E5 Human

Unigene: 647084 Human



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