Product Name	DRG1
Chinese Name	GTP发育调控Binding protein1抗体
Alias	Developmentally regulated GTP binding protein 1; Developmentally-regulated GTP-binding protein 1; DRG 1; DRG-1; DRG1; DRG1_HUMAN; NEDD 3; NEDD-3; NEDD3; Neural precursor cell expressed developmentally down regulated protein 3; Neural precursor cell expressed developmentally down-regulated protein 3.
Research Area	Tumour  Cell biology  immunology  Developmental biology  Signal transduction  Cyclin  transcriptional regulatory factor  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Cow, Horse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	41kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DRG1: 301-367/367
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	May play a role in cell proliferation, differentiation and death.High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes. Function: Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest. Subunit: Interacts (via its C-terminal) with TAL1. Interacts with ZC3H15; the interaction forms a polysomal DRG1-DFRP1/ZC3H15 complex which provides protein stability to DRG1 possibly by blocking poly-ubiquitination. Interacts with STK16; the interaction phosphorylates STK16 Subcellular Location: Cytoplasm. Note=The DRG1-DFRP2/ZC3H15 complex associates with polysomes. Tissue Specificity: High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes. Post-translational modifications: Sumoylated by UBE2I in response to MEKK1-mediated stimuli. Similarity: Belongs to the GTP1/OBG family. Contains 1 G (guanine nucleotide-binding) domain. SWISS: Q9Y295 Gene ID: 4733 Database links: Entrez Gene: 4733 Human Entrez Gene: 13494 Mouse Entrez Gene: 305470 Rat Omim: 603952 Human SwissProt: Q9Y295 Human SwissProt: P32233 Mouse SwissProt: Q5I0F0 Rat Unigene: 115242 Human Unigene: 3250 Mouse Unigene: 102143 Rat

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