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Product Name RHD Polypeptide Chinese Name Rh polypeptide 2抗体 Alias Blood group Rh(D) polypeptide; Blood group--Rhesus system D polypeptide; CD240D; D antigen (DCS); DIIIc; MGC165007; RH; Rh blood group antigen Evans; Rh blood group D antigen; Rh polypeptide 2; RH30; Rh4; RHCED; Rhd; RHD_HUMAN; RhDCw; RHDel; RHDVA(TT); Rhesus blood group D antigen allele DIII type 7; Rhesus D antigen; Rhesus system D polypeptide; RhII; RhK562-II; RhPI. Research Area Cell biology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 45kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human RhD: 21-120/417 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function:
May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane.
Subcellular Location:
Membrane.
Tissue Specificity:
Restricted to tissues or cell lines expressing erythroid characters.
Similarity:
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
SWISS:
Q02161
Gene ID:
6007
Database links:
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