Product Name	GRTP1
Chinese Name	生长激素调节TBC蛋白1抗体
Alias	FLJ22474; Growth hormone-regulated TBC protein 1; Grtp1; GRTP1_HUMAN; MGC138328; MGC138330; OTTHUMP00000018752; TBC1 domain family member 6; TBC1 domain family, member 6; TBC1D6.
Research Area	Cell biology  Signal transduction  Growth factors and hormones  G protein-coupled receptor  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	39kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GRTP1: 231-336/336
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	GRTP1 is a 336 amino acid protein with expression modulated by growth hormone. The TBC1 domain of GRTP1 is a region that is notably conserved among GTPase-activating proteins, which characteristically play a role in the cell cycle and mitosis coordination. Interestingly, expression of GRTP1 is significantly upregulated in post-puberty testis and then maintained in the adult, suggesting that the germ cell may be the major site of GRTP1 function. There are two isoforms of GRTP1, which are a result of alternative splicing events. Function: May act as a GTPase-activating protein for Rab family protein(s). Similarity: Contains 1 Rab-GAP TBC domain. SWISS: Q5TC63 Gene ID: 79774 Database links: Entrez Gene: 79774 Human Entrez Gene: 66790 Mouse Entrez Gene: 361180 Rat SwissProt: Q5TC63 Human SwissProt: Q9D3N8 Mouse SwissProt: Q4QQU7 Rat Unigene: 170904 Human Unigene: 34901 Mouse Unigene: 19589 Rat

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