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Product Name CTAGE1 Chinese Name 皮肤T细胞淋巴瘤相关抗原1抗体 Alias Cancer/testis antigen 21.2; Cancer/testis antigen family 21 member 1; Cancer/testis antigen family 21 member 2; CT21.2; CTAGE 1; CTAGE 2; CTAGE; CTAGE1; CTGE2_HUMAN; Cutaneous T cell lymphoma associated antigen 1; Cutaneous T cell lymphoma associated antigen 2; Protein cTAGE-2. Research Area Tumour Cell biology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 85kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human CTAGE1: 151-250/745 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Cutaneous T-cell lymphoma-associated antigen 1 (CTAGE1) is normally expressed only in testis tissue, and is found in 35% of CTCL tissues, but not in any leukemia or melanoma cell lines. The gene encoding for CTAGE1 maps to chromosome 18p11.2. CTAGE2 is a longer variant of CTAGE1 and is translated from a different open reading frame. Three other splice variants related to the major CTAGE1 and CTAGE2 variants exist, some of which are expressed only in testis, while others are expressed in a wide range of adult and fetal tissues. CTAGE1 may be an important factor in the specific immunotherapy of cutaneous T-cell lymphoma and other malignancies.
Subcellular Location:
Membrane.
Tissue Specificity:
Testis. Not found in tumor.
Similarity:
Belongs to the cTAGE family.
SWISS:
Q96RT6
Gene ID:
64693
Database links:Entrez Gene: 64693 Human
Omim: 608856 Human
SwissProt: Q96RT6 Human
Unigene: 406709 Human
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