Product Name	BVDV E2
Chinese Name	牛病毒性腹泻病毒1型E2蛋白抗体
Alias	polyprotein [Bovine viral diarrhea virus 1]; POLG_BVDVN; Envelope glycoprotein E2; BVDV Envelope glycoprotein E2; PestiV1gp1 polyprotein [ Bovine viral diarrhea virus 1 ].  牛病毒性腹泻病毒1型;
literatures	Specific References  (2)     |     SL20022R has been referenced in 2 publications. [IF=8.786] Mi Shijiang. et al. Characterization of monoclonal antibodies that specifically differentiate field isolates from vaccine strains of classical swine fever virus. FRONT IMMUNOL. 2022 Jul;0:3835  IFA ;  Pig.   PubMed:35958565 [IF=5.913] Cheng, Jinghua. et al. Coinfection with PEDV and BVDV induces inflammatory bowel disease pathway highly enriched in PK-15 cells. VIROL J. 2022 Dec;19(1):1-12  IF, WB ;  Pig.   PubMed:35842726
Research Area	Bacteria and viruses
Immunogen Species	Rabbit
Clonality	Polyclonal
Applications	ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	45kDa
Form	Liquid
Concentration	1mg/ml
immunogen	Recombinded BVDV Envelope glycoprotein E2: full length protein
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Initial binding to target cell probably involves interaction of E(rns) with glycosaminoglycans. E1 and/or E2 are responsible of cell attachment with CD46 and subsequent fusion after internalization of the virion by endocytosis (Probable). P7 forms a leader sequence to properly orient NS2 in the membrane. Uncleaved NS2-3 is required for production of infectious virus. NS2 protease seems to play a vital role in viral RNA replication control and in the pathogenicity of the virus. NS3 displays three enzymatic activities: serine protease, NTPase and RNA helicase. NS4A is a cofactor for the NS3 protease activity. RNA-directed RNA polymerase NS5 replicates the viral (+) and (-) genome. SWISS: P19711 Gene ID: 1489735 Database links: Entrez Gene: 1489735 BVDV

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