Product Name	EML2
Chinese Name	EML2蛋白抗体
Alias	1600029N02Rik; Echinoderm microtubule associated protein like 2; Echinoderm microtubule-associated protein-like 2; Echinoderm MT associated protein like protein 70; ELP70; EMAL2_HUMAN; EMAP-2; EMAP2; EML2; HuEMAP-2.
Research Area	Cell biology  Neurobiology  Signal transduction  Apoptosis  Cytoskeleton
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	71kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human EML2: 561-649/649
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Microtubules are components of the actin cytoskeleton that play crucial roles in cell morphogenesis, cell motility, spindle formation and chromosome movements. Echinoderm microtubule-associated (EML) proteins function to modify the assembly dynamics of microtubules. EML2 (echinoderm microtubule associated protein like 2), also known as ELP70, EMAP2 or EMAPL2, is a cytoplasmic protein that acts to elongate microtubules, while at the same time making them more dynamic. Like other members of the EML family, EML2 contains a hydrophobic ELP (HELP) domain and a large WD repeat domain, both of which allow EML2 to participate in cytoskeleton assembly. Function: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic. Subcellular Location: Cytoplasm; cytoskeleton. Tissue Specificity: Ubiquitous. Similarity: Belongs to the WD repeat EMAP family. Contains 11 WD repeats. SWISS: O95834 Gene ID: 24139 Database links: Entrez Gene: 24139 Human Entrez Gene: 72205 Mouse Entrez Gene: 192360 Rat SwissProt: O95834 Human SwissProt: Q7TNG5 Mouse SwissProt: Q6P6T4 Rat Unigene: 24178 Human Unigene: 154121 Mouse Unigene: 76362 Rat

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