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Product Name PCDH19 Chinese Name 原钙粘附蛋白19抗体 Alias KIAA1313; PCD19_HUMAN; PCDH19; Protocadherin 19; Protocadherin-19. Research Area Cell biology Cell adhesion molecule The cell membrane蛋白 Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, ) Applications WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 124kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human PCDH19: 151-250/1148 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene is a member of the delta-2 protocadherin subclass of the cadherin superfamily. The encoded protein is thought to be a calcium-dependent cell-adhesion protein that is primarily expressed in the brain. Defects in this gene are a cause of epilepsy female-restricted with mental retardation (EFMR). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]
Function:
Potential calcium-dependent cell-adhesion protein.
Subcellular Location:
Cell membrane.
Tissue Specificity:
Moderately expressed in all regions of the brain examined, with lowest levels found in the cerebellum. Moderate expression is also found in ovary, and low expression in all other tissues tested. Also detected in primary skin fibroblast.
DISEASE:
Epileptic encephalopathy, early infantile, 9
Similarity:
Contains 6 cadherin domains.
SWISS:
Q8TAB3
Gene ID:
57526
Database links:Entrez Gene: 57526 Human
Entrez Gene: 101125719 Gorilla
Entrez Gene: 100059478 Horse
Entrez Gene: 279653 Mouse
Omim: 300460 Human
SwissProt: Q8TAB3 Human
SwissProt: Q80TF3 Mouse
Unigene: 4993 Human
Unigene: 39738 Mouse
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