TEL: +86 571 56623320 EMAIL: [email protected]
Product Name PATL1 Chinese Name PATL1蛋白抗体 Alias hPat1b; OK/KNS-cl.5; PAT1-like protein 1; Pat1b; PATL1; PATL1_HUMAN; protein associated with topoisomerase II homolog 1; Protein PAT1 homolog 1; Protein PAT1 homolog b. Research Area Cell biology Transporter Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 87kDa Cellular localization The nucleus cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human PATL1: 351-450/770 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly. In case of infection, required for translation and replication of hepatitis C virus (HCV).
Subunit:
Interacts (via region A) with DDX6/RCK. Interacts (via region H and region C) with LSM1 and LSM4. Interacts (via region N) with DCP1A, DCP2, EDC3, EDC4 and XRN1. Interacts with the CCR4-NOT complex. Interacts with the Lsm-containing SMN-Sm protein complex.
Subcellular Location:
Cytoplasm > P-body.
Tissue Specificity:
Ubiquitous.
Similarity:
Belongs to the PAT1 family.
SWISS:
Q86TB9
Gene ID:
219988
Database links:Entrez Gene: 219988 Human
Entrez Gene: 225929 Mouse
SwissProt: Q86TB9 Human
SwissProt: Q3TC46 Mouse
Unigene: 591960 Human
Unigene: 42711 Mouse
Scan Wechat Qrcode