Product Name	RHOD
Chinese Name	RHOD蛋白抗体
Alias	ARHD; Ras homolog D; Ras homolog gene family member A; Ras homolog gene family member D; Rho; RHO D; Rho related GTP binding protein RhoD; Rho related protein HP1; Rho-related GTP-binding protein RhoD; Rho-related protein HP1; RHOD; RHOD_HUMAN; RhoHP1; RHOM.
Research Area	Cell biology  Signal transduction  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Rat,  (predicted: Human, Mouse, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	23kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human RHOD: 21-100/210
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a critical role in muscle differentiation. The protein encoded by this gene binds GTP and is a member of the small GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] Function: Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Participates in reorganization of actin cytoskeleton. Subunit: Interacts (in GTP-bound form) with DIAPH2 isoform 3, DAPK3, FILIP1 and WHAMM. Interacts with PAK7/PAK5. Interacts (independent of GTP-loaded status) with ANKFY1. Subcellular Location: Cell membrane. Tissue Specificity: Heart, placenta, liver, skeletal muscle, and pancreas and, with weaker intensity, in several other tissues. Similarity: Belongs to the small GTPase superfamily. Rho family. SWISS: O00212 Gene ID: 29984 Database links: Entrez Gene: 29984 Human Entrez Gene: 11854 Mouse Entrez Gene: 293660 Rat Omim: 605781 Human SwissProt: O00212 Human SwissProt: P97348 Mouse Unigene: 15114 Human Unigene: 27701 Mouse

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