Product Name	RGS8
Chinese Name	G protein signal转导调节因子8抗体
Alias	Regulator of G Protein Signalling 8; Regulator of G-protein signaling 8; RGS8; RGS8_HUMAN.
Research Area	Cell biology  Signal transduction  G protein-coupled receptor  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Cow, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	21kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human RGS8: 1-100/180
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene is a member of the regulator of G protein signaling (RGS) family and encodes a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, also accelerate receptor-stimulated activation. [provided by RefSeq, Jul 2008] Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Preferentially binds to G(o)-alpha and G(i)-alpha-3. Subcellular Location: Cytoplasm. Similarity: Contains 1 RGS domain. SWISS: P57771 Gene ID: 85397 Database links: Entrez Gene: 85397 Human Entrez Gene: 67792 Mouse Entrez Gene: 54297 Rat Omim: 607189 Human SwissProt: P57771 Human SwissProt: Q8BXT1 Mouse SwissProt: P49804 Rat Unigene: 20982 Human Unigene: 458417 Human Unigene: 379143 Mouse Unigene: 89634 Rat

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