TEL: +86 571 56623320 EMAIL: [email protected]
Product Name SLC39A5 Chinese Name 溶质载体家族蛋白39成员A5抗体 Alias LZT Hs7; MGC34778; OTTHUMP00000211153; OTTHUMP00000211154; S39A5_HUMAN; SLC39A5; solute carrier family 39 (metal ion transporter), member 5; Solute carrier family 39 member 5; Zinc transporter ZIP5 [Precursor]; Zinc transporter ZIP5; ZIP 5; ZIP-5; ZIP5; Zrt and Irt like protein 5; Zrt- and Irt-like protein 5. Research Area Tumour Cell biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Cat, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 57kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SLC39A5: 21-100/540 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene belongs to the ZIP family of zinc transporters that transport zinc into cells from outside, and play a crucial role in controlling intracellular zinc levels. Zinc is an essential cofactor for many enzymes and proteins involved in gene transcription, growth, development and differentiation. Mutations in this gene have been associated with autosomal dominant high myopia (MYP24). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]
Function:
May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Seems to play a central role in controlling organismal zinc status.
Subcellular Location:
Basolateral cell membrane.
Tissue Specificity:
Expressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney.
Post-translational modifications:
Glycosylated.
Similarity:
Belongs to the ZIP transporter (TC 2.A.5) family.
SWISS:
Q6ZMH5
Gene ID:
283375
Database links:Entrez Gene: 283375 Human
Entrez Gene: 72002 Mouse
GenBank: NM_173596 Human
Omim: 608730 Human
SwissProt: Q6ZMH5 Human
SwissProt: Q9D856 Mouse
Unigene: 591018 Human
Unigene: 22983 Mouse
Scan Wechat Qrcode