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Product Name SLC39A14 Chinese Name 溶质载体家族蛋白39成员A14抗体 Alias Cig19; KIAA0062; LIV-1 subfamily of ZIP zinc transporter 4; LZT-Hs4; NET34; S39AE_HUMAN; SLC39A14; Solute carrier family 39 (zinc transporter), member 14; Solute carrier family 39 member 14; Zinc transporter ZIP14; ZIP-14; ZIP14; Zrt Irt like protein 14; Zrt- and Irt-like protein 14. Research Area Cell biology immunology Developmental biology Signal transduction Cell differentiation Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Chimpanzee, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 51kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SLC39A14: 51-150/492 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A14 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]
Function:
May be able to transport iron (By similarity). Acts as a zinc-influx transporter.
Subunit:
Homotrimer.
Subcellular Location:
Cell membrane. Cell projection > lamellipodium. Localized to the plasma membrane and also found colocalized with F-actin concentrated on lamellipodiae.
Tissue Specificity:
Ubiquitously expressed, with increased expression in liver, pancreas, fetal liver, thyroid gland, left and right ventricle, right atrium and fetal heart. Weakly expressed in spleen, thymus, and peripheral blood leukocytes.
Similarity:
Belongs to the ZIP transporter (TC 2.A.5) family.
SWISS:
Q15043
Gene ID:
23516
Database links:Entrez Gene: 464044 Chimpanzee
Entrez Gene: 23516 Human
Entrez Gene: 100387296 Marmoset (common)
Entrez Gene: 213053 Mouse
Entrez Gene: 100172692 Orangutan
Omim: 608736 Human
SwissProt: Q15043 Human
SwissProt: Q75N73 Mouse
SwissProt: Q5RAB7 Orangutan
Unigene: 491232 Human
Unigene: 270647 Mouse
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