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Rabbit Anti-SLC39A14 antibody
Rabbit Anti-SLC39A14 antibody
Cig19; KIAA0062; LIV-1 subfamily of ZIP zinc transporter 4; LZT-Hs4; NET34; S39AE_HUMAN; SLC39A14; Solute carrier family 39 (zinc transporter), member 14; Solute carrier family 39 member 14; Zinc transporter ZIP14; ZIP-14; ZIP14; Zrt Irt like protein 14;
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  • NO.:SL19829R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Chimpanzee,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name SLC39A14
Chinese Name 溶质载体家族蛋白39成员A14抗体
Alias Cig19; KIAA0062; LIV-1 subfamily of ZIP zinc transporter 4; LZT-Hs4; NET34; S39AE_HUMAN; SLC39A14; Solute carrier family 39 (zinc transporter), member 14; Solute carrier family 39 member 14; Zinc transporter ZIP14; ZIP-14; ZIP14; Zrt Irt like protein 14; Zrt- and Irt-like protein 14.  
Research Area Cell biology  immunology  Developmental biology  Signal transduction  Cell differentiation  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Chimpanzee, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 51kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human SLC39A14: 51-150/492 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A14 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]

Function:
May be able to transport iron (By similarity). Acts as a zinc-influx transporter.

Subunit:
Homotrimer.

Subcellular Location:
Cell membrane. Cell projection > lamellipodium. Localized to the plasma membrane and also found colocalized with F-actin concentrated on lamellipodiae.

Tissue Specificity:
Ubiquitously expressed, with increased expression in liver, pancreas, fetal liver, thyroid gland, left and right ventricle, right atrium and fetal heart. Weakly expressed in spleen, thymus, and peripheral blood leukocytes.

Similarity:
Belongs to the ZIP transporter (TC 2.A.5) family.

SWISS:
Q15043

Gene ID:
23516

Database links:

Entrez Gene: 464044 Chimpanzee

Entrez Gene: 23516 Human

Entrez Gene: 100387296 Marmoset (common)

Entrez Gene: 213053 Mouse

Entrez Gene: 100172692 Orangutan

Omim: 608736 Human

SwissProt: Q15043 Human

SwissProt: Q75N73 Mouse

SwissProt: Q5RAB7 Orangutan

Unigene: 491232 Human

Unigene: 270647 Mouse



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