Product Name	SLC34A3
Chinese Name	溶质载体家族蛋白34成员A3抗体
Alias	HHRH; Na(+) dependent phosphate cotransporter 2C; Na(+) Pi cotransporter 2C; Na(+)-dependent phosphate cotransporter 2C; Na(+)/Pi cotransporter 2C; NaPi 2c; NaPi-2c; NPT2C; NPT2C_HUMAN; NPTIIC; SLC34A3; Sodium dependent phosphate transport protein 2C; Sodium inorganic phosphate cotransporter IIC; Sodium phosphate cotransporter 2C; Sodium phosphate transport protein 2C; Sodium-dependent phosphate transport protein 2C; Sodium-phosphate transport protein 2C; Sodium/inorganic phosphate cotransporter IIC; Sodium/inorganic phosphate cotransporter, type IIC; Sodium/phosphate cotransporter 2C; solute carrier family 34 (sodium phosphate) member 3; solute carrier family 34 (sodium/phosphate contransporter), member 3; solute carrier family 34 (type II sodium/phosphate contransporter), member 3; Solute carrier family 34 member 3; type IIc Na+ Pi cotransporter.
Research Area	Tumour  Cell biology  Signal transduction  Transporter
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	63kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SLC34A3: 251-350/599 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of SLC34A transporter family of proteins, and is expressed primarily in the kidney. It is involved in transporting phosphate into cells via sodium cotransport in the renal brush border membrane, and contributes to the maintenance of inorganic phosphate concentration in the kidney. Mutations in this gene are associated with hereditary hypophosphatemic rickets with hypercalciuria. Alternatively spliced transcript variants varying in the 5' UTR have been found for this gene.[provided by RefSeq, Apr 2010] Function: May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 20-30% of the apical influx. Subcellular Location: Membrane. DISEASE: Hereditary hypophosphatemic rickets with hypercalciuria. Similarity: Belongs to the SLC34A transporter family. SWISS: Q8N130 Gene ID: 142680 Database links: Entrez Gene: 142680 Human Entrez Gene: 142681 Mouse Entrez Gene: 246234 Rat Omim: 609826 Human SwissProt: Q8N130 Human SwissProt: Q80SU6 Mouse SwissProt: Q8K4R8 Rat Unigene: 432442 Human Unigene: 346652 Mouse Unigene: 490356 Mouse Unigene: 15318 Rat

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