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Rabbit Anti-SLC20A1 antibody
Rabbit Anti-SLC20A1 antibody
DKFZp686J2397; FLJ41426; Gibbon ape leukemia virus receptor 1; GLVR 1; GLVR-1; GLVR1; Leukemia virus receptor 1 homolog; Phosphate transporter 1; PIT 1; PiT-1; PIT1; S20A1_HUMAN; Slc20a1; Sodium dependent phosphate transporter 1; Sodium-dependent phosphat
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  • NO.:SL19804R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
    Applications:IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name SLC20A1
Chinese Name 溶质载体家族蛋白20成员A1抗体
Alias DKFZp686J2397; FLJ41426; Gibbon ape leukemia virus receptor 1; GLVR 1; GLVR-1; GLVR1; Leukemia virus receptor 1 homolog; Phosphate transporter 1; PIT 1; PiT-1; PIT1; S20A1_HUMAN; Slc20a1; Sodium dependent phosphate transporter 1; Sodium-dependent phosphate transporter 1; Solute carrier family 20 (phosphate transporter) member 1; Solute carrier family 20 member 1.  
Research Area Tumour  Cell biology  Signal transduction  The cell membrane蛋白  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 74kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human SLC20A1: 401-500/679 <Cytoplasmic>
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail The protein encoded by this gene is a sodium-phosphate symporter that absorbs phosphate from interstitial fluid for use in cellular functions such as metabolism, signal transduction, and nucleic acid and lipid synthesis. The encoded protein is also a retroviral receptor, causing human cells to be susceptible to infection by gibbon ape leukemia virus, simian sarcoma-associated virus, feline leukemia virus subgroup B, and 10A1 murine leukemia virus.[provided by RefSeq, Mar 2011]

Function:
Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport, such as absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification. May function as a retroviral receptor as it confers human cells susceptibility to infection to Gibbon Ape Leukemia Virus (GaLV), Simian sarcoma-associated virus (SSAV) and Feline leukemia virus subgroup B (FeLV-B) as well as 10A1 murine leukemia virus (10A1 MLV).

Subcellular Location:
Membrane.

Tissue Specificity:
Ubiquitously expressed.

Similarity:
Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.

SWISS:
Q8WUM9

Gene ID:
6574

Database links:

Entrez Gene: 493789 Cat

Entrez Gene: 514255 Cow

Entrez Gene: 6574 Human

Entrez Gene: 100173250 Orangutan

Entrez Gene: 81826 Rat

Omim: 137570 Human

SwissProt: O97596 Cat

SwissProt: Q8WUM9 Human

SwissProt: Q5R9L5 Orangutan

SwissProt: Q9JJP0 Rat

Unigene: 187946 Human

Unigene: 732750 Human

Unigene: 162702 Rat



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