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Rabbit Anti-SLC13A5 antibody
Rabbit Anti-SLC13A5 antibody
Na(+)/citrate cotransporter; EIEE25; NaC2/NaCT; NaCT; Novel solute carrier family 13 (sodium dependent dicarboxylate transporter) (Slc13a2 or 3) member; S13A5_HUMAN; Slc13a5; Sodium coupled citrate transporter; Sodium-coupled citrate transporter; Sodium-d
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  • NO.:SL19796R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Pig,Rabbit,Sheep,)
    Applications:ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name SLC13A5
Chinese Name 溶质载体家族蛋白13成员A5抗体
Alias Na(+)/citrate cotransporter; EIEE25; NaC2/NaCT; NaCT; Novel solute carrier family 13 (sodium dependent dicarboxylate transporter) (Slc13a2 or 3) member; S13A5_HUMAN; Slc13a5; Sodium coupled citrate transporter; Sodium-coupled citrate transporter; Sodium-dependent citrate transporter; Solute carrier family 13 (sodium dependent citrate transporter), member 5; Solute carrier family 13 member 5.  
literatures
Specific References  (1)     |     SL19796R has been referenced in 1 publications.
[IF=4.772] Lei Yang. et al. Comprehensive comparative analysis of histopathology and gene expression in subchondral bone between kashin-beck disease and primary osteoarthritis. FRONT GENET. 2022; 13: 942326  IHC ;  Human.  
Research Area Tumour  Cell biology  Signal transduction  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Pig, Rabbit, Sheep, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 63kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human SLC13A5: 331-430/568 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene encodes a protein belonging to the solute carrier family 13 group of proteins. This family member is a sodium-dependent citrate cotransporter that may regulate metabolic processes. Mutations in this gene cause early infantile epileptic encephalopathy 25. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]

Function:
High-affinity sodium/citrate cotransporter that mediates citrate entry into cells. The transport process is electrogenic; it is the trivalent form of citrate rather than the divalent form that is recognized as a substrate. May facilitate the utilization of circulating citrate for the generation of metabolic energy and for the synthesis of fatty acids and cholesterol.

Subcellular Location:
Membrane.

Tissue Specificity:
Expressed most predominantly in the liver, with moderate expression detectable in the brain and testis.

Similarity:
Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily.

SWISS:
Q86YT5

Gene ID:
284111

Database links:

Entrez Gene: 284111 Human

Entrez Gene: 237831 Mouse

Omim: 608305 Human

SwissProt: Q86YT5 Human

SwissProt: Q67BT3 Mouse

Unigene: 399496 Human

Unigene: 340778 Mouse



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