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Product Name SLC13A5 Chinese Name 溶质载体家族蛋白13成员A5抗体 Alias Na(+)/citrate cotransporter; EIEE25; NaC2/NaCT; NaCT; Novel solute carrier family 13 (sodium dependent dicarboxylate transporter) (Slc13a2 or 3) member; S13A5_HUMAN; Slc13a5; Sodium coupled citrate transporter; Sodium-coupled citrate transporter; Sodium-dependent citrate transporter; Solute carrier family 13 (sodium dependent citrate transporter), member 5; Solute carrier family 13 member 5. literatures Specific References (1) | SL19796R has been referenced in 1 publications.[IF=4.772] Lei Yang. et al. Comprehensive comparative analysis of histopathology and gene expression in subchondral bone between kashin-beck disease and primary osteoarthritis. FRONT GENET. 2022; 13: 942326 IHC ; Human.Research Area Tumour Cell biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Rabbit, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 63kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SLC13A5: 331-430/568 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a protein belonging to the solute carrier family 13 group of proteins. This family member is a sodium-dependent citrate cotransporter that may regulate metabolic processes. Mutations in this gene cause early infantile epileptic encephalopathy 25. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]
Function:
High-affinity sodium/citrate cotransporter that mediates citrate entry into cells. The transport process is electrogenic; it is the trivalent form of citrate rather than the divalent form that is recognized as a substrate. May facilitate the utilization of circulating citrate for the generation of metabolic energy and for the synthesis of fatty acids and cholesterol.
Subcellular Location:
Membrane.
Tissue Specificity:
Expressed most predominantly in the liver, with moderate expression detectable in the brain and testis.
Similarity:
Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily.
SWISS:
Q86YT5
Gene ID:
284111
Database links:Entrez Gene: 284111 Human
Entrez Gene: 237831 Mouse
Omim: 608305 Human
SwissProt: Q86YT5 Human
SwissProt: Q67BT3 Mouse
Unigene: 399496 Human
Unigene: 340778 Mouse
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