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Product Name SLC10A6 Chinese Name 溶质载体家族蛋白10成员A6抗体 Alias MGC129575; MGC129576; Slc10a6; SOAT; SOAT_HUMAN; Sodium dependent organic anion transporter; Sodium-dependent organic anion transporter; Solute carrier family 10 member 6. Research Area Tumour Cell biology Signal transduction The cell membrane蛋白 Immunogen Species Rabbit Clonality Polyclonal React Species Human, Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 42kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SLC10A6: 301-377/377 <Cytoplasmic> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail SLC10A6 (Solute Carrier Family 10 Member 6) is a Protein Coding gene. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. GO annotations related to this gene include bile acid:sodium symporter activity and sodium-dependent organic anion transmembrane transporter activity. An important paralog of this gene is SLC10A2.
Function:
Transports sulfoconjugated steroid hormones, as well as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes in a sodium-dependent manner.
Subcellular Location:
Membrane.
Tissue Specificity:
Highly expressed in testis, placenta and pancreas. Moderately expressed in heart, lung and mammary gland. Weakly expressed in brain, colon, kidney, liver, ovary, prostate, small intestine, spleen and thymus.
Post-translational modifications:
Glycosylated.
Similarity:
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
SWISS:
Q3KNW5
Gene ID:
345274
Database links:Entrez Gene: 345274 Human
GenBank: NM_197965 Human
SwissProt: Q3KNW5 Human
Unigene: 452996 Human
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