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Product Name RAB5C Chinese Name ras基因相关蛋白RAB5C抗体 Alias L1880; RAB, member of RAS oncogene family like; RAB5C; RAB5C, member of RAS oncogene family; RAB5C, member RAS oncogene family; RAB5C_HUMAN; RAB5CL; RAB5L; RABL; Ras-related protein Rab-5C. Research Area Cell biology Signal transduction G protein-coupled receptor G protein signal Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 23kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human RAB5C: 151-250/216 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]).[supplied by OMIM, Nov 2010]
Function:
Protein transport. Probably involved in vesicular traffic.
Subcellular Location:
Cell membrane. Early endosome membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Similarity:
Belongs to the small GTPase superfamily. Rab family.
SWISS:
P51148
Gene ID:
5878
Database links:Entrez Gene: 5878 Human
Entrez Gene: 19345 Mouse
Omim: 604037 Human
SwissProt: P51148 Human
SwissProt: P35278 Mouse
Unigene: 650382 Human
Unigene: 29829 Mouse
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