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Product Name RBMXL2 Chinese Name RBMXL2蛋白抗体 Alias Heterogeneous nuclear ribonucleoprotein G T; hnRNP G T; hnRNP G-T; HNRNPG T; HNRNPGT; HNRPGT; RBMX L2; RBMXL 2; RBMXL2; RMXL2_HUMAN; RNA binding motif protein X linked like 2; RNA-binding motif protein; Testes specific heterogenous nuclear ribonucleoprotein G T; Testis-specific heterogeneous nuclear ribonucleoprotein G-T; X-linked-like-2. Research Area Cell biology Developmental biology Binding protein Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 43kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human RBMXL2: 221-320/392 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind RNAs. This gene is intronless and is thought to be derived from a processed retroposon. However, unlike many retroposon-derived genes, this gene is not a pseudogene. The encoded protein has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility. [provided by RefSeq, Jul 2008]
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed predominantly in spermatocytes and less in round spermatids (at protein level). Expressed in germ cells.
Similarity:
Contains 1 RRM (RNA recognition motif) domain.
SWISS:
O75526
Gene ID:
27288
Database links:Entrez Gene: 27288 Human
Entrez Gene: 76572 Mouse
Omim: 605444 Human
SwissProt: O75526 Human
Unigene: 121605 Human
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