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Rabbit Anti-Matrilin 1 antibody
Rabbit Anti-Matrilin 1 antibody
Cartilage matrix protein; CMP; CRTM; Mat1; MATN1; Matrilin-1; MGC95132; Cartilage matrix protein 1.
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  • NO.:SL1976R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Horse,Rabbit,)
    Applications:WB ELISA IHC-P IHC-F IF
    concentration:1mg/ml
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Product Name Matrilin 1
Chinese Name 软骨基质蛋白抗体
Alias Cartilage matrix protein; CMP; CRTM; Mat1; MATN1; Matrilin-1; MGC95132; Cartilage matrix protein 1.  
Research Area immunology  Developmental biology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Horse, Rabbit, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 55kDa
Cellular localization Extracellular matrix Secretory protein 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human Matrilin 1: 301-400/496 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene encodes a member of von Willebrand factor A domain containing protein family. This family of proteins are thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. Mutations of this gene have been associated with variety of inherited chondrodysplasias. [provided by RefSeq]

Function:
Cartilage matrix protein is a major component of the extracellular matrix of non-articular cartilage. It binds to collagen.

Subunit:
Homotrimer. Interacts with COMP.

Subcellular Location:
Secreted, extracellular space, extracellular matrix.

Similarity:
Contains 1 EGF-like domain.
Contains 2 VWFA domains.

SWISS:
P21941

Gene ID:
4146

Database links:

Entrez Gene: 4146 Human

Entrez Gene: 17180 Mouse

Entrez Gene: 297894 Rat

Omim: 115437 Human

SwissProt: P21941 Human

SwissProt: P51942 Mouse

Unigene: 150366 Human

Unigene: 271796 Mouse

Unigene: 15159 Rat



Matrilins 是一组非胶原的Extracellular matrix蛋白家族,该蛋白家族分别为 Matrilin-1, Matrilin-2, Matrilin-3 和 Matrilin-4 。
Matrilnin-1 和 Matrilin-3 主要分布在生长的软骨组织中,Matrilin-2 和 Matrilin-4 分布较广,主要分布于软骨的增殖和肥大区,在软骨膜、骨膜及骨组织中,而且,它也分布在许多非骨组织中,如腱、韧带、真皮、心脏、平滑肌、消化道和呼吸道等。

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