Product Name	SEC23IP
Chinese Name	SEC23相互作用蛋白抗体
Alias	CDA II; CDAII; CDAN2; HEMPAS; Protein transport protein Sec23B; RP11-379J5.1; SC23B_HUMAN; Sec23 homolog B (S. cerevisiae); SEC23 related protein B; SEC23-like protein B; SEC23-related protein B; Sec23b; Transport protein SEC23B.
Research Area	Tumour  Cell biology  Developmental biology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Rat, Rabbit, Sheep,  (predicted: Human, Mouse, Cow, Horse, )
Applications	IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	111kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SEC23IP: 811-910/1000
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the phosphatidic acid preferring-phospholipase A1 family. The encoded protein is localized to endoplasmic reticulum exit sites and plays a critical role in ER-Golgi transport as part of the multimeric coat protein II complex. An orthologous gene in frogs is required for normal neural crest cell development, suggesting that this gene may play a role in Waardenburg syndrome neural crest defects. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011] Function: Plays a role in the organization of endoplasmic reticulum exit sites. Subcellular Location: Cytoplasmic vesicle > COPII-coated vesicle membrane. Endoplasmic reticulum. Tissue Specificity: Ubiquitously expressed with stronger levels detected in heart, liver and skeletal muscle. Similarity: Belongs to the PA-PLA1 family. Contains 1 DDHD domain. Contains 1 SAM (sterile alpha motif) domain. SWISS: Q9Y6Y8 Gene ID: 11196 Database links: Entrez Gene: 11196 Human Entrez Gene: 207352 Mouse Entrez Gene: 309010 Rat SwissProt: Q9Y6Y8 Human SwissProt: Q6NZC7 Mouse Unigene: 435004 Human Unigene: 667094 Human Unigene: 297105 Mouse

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