Product Name	SDPR
Chinese Name	磷脂酰丝氨酸Binding proteinSDPR抗体
Alias	Cavin 2; Cavin-2; Phosphatidylserine binding protein; Phosphatidylserine-binding protein; PS p68; PS-p68; Sdpr; SDPR_HUMAN; SDR; Serum deprivation response; Serum deprivation response protein; Serum deprivation-response protein.
Research Area	Cell biology  Signal transduction  Kinases and Phosphatases  Binding protein
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse, Rat,  (predicted: Human, Cow, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	47kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SDPR: 231-330/425
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.[provided by RefSeq, Sep 2009] Function: May play a role in targeting PRKCA to caveolae. Subcellular Location: Cytoplasm > cytosol. Membrane > caveola. Colocalizes with CAV1 to caveolae. Tissue Specificity: Highly expressed in heart and lung, and expressed at lower levels in brain, kidney, liver, pancreas, placenta, and skeletal muscle. Post-translational modifications: Phosphorylated on Ser residues. Similarity: Belongs to the PTRF/SDPR family. SWISS: O95810 Gene ID: 8436 Database links: Entrez Gene: 8436 Human Entrez Gene: 20324 Mouse Entrez Gene: 316384 Rat Omim: 606728 Human SwissProt: O95810 Human SwissProt: Q63918 Mouse SwissProt: Q66H98 Rat Unigene: 26530 Human Unigene: 480575 Mouse Unigene: 203035 Rat
Product Picture	Protein: heart(mouse) lysate at 40ug; Primary: rabbit Anti-SDPR (SL19605R) at 1:300; Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 47 kD Observed band size: 47 kD Paraformaldehyde-fixed, paraffin embedded (Rat heart); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SDPR) Polyclonal Antibody, Unconjugated (SL19605R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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