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Product Name SCRN1 Chinese Name 分离蛋白SCRN1抗体 Alias KIAA0193; OTTHUMP00000202313; SCRN 1; SCRN1; SCRN1_HUMAN; Secernin 1; Secernin-1; Secernin1; SES1. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 46kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SCRN1: 151-250/414 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene likely encodes a member of the secernin family of proteins. A similar protein in rat functions in regulation of exocytosis in mast cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]
Function:
Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium.
Subcellular Location:
Cytoplasm.
Similarity:
Belongs to the peptidase C69 family. Secernin subfamily.
SWISS:
Q12765
Gene ID:
9805
Database links:Entrez Gene: 9805 Human
Entrez Gene: 69938 Mouse
Omim: 614965 Human
SwissProt: Q12765 Human
SwissProt: Q9CZC8 Mouse
Unigene: 520740 Human
Unigene: 41557 Mouse
Unigene: 154317 Rat
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