Product Name	NUDT14
Chinese Name	NUDT14蛋白抗体
Alias	Nucleoside diphosphate linked moiety X type motif 14; Nucleoside diphosphate-linked moiety X motif 14; NUD14_HUMAN; Nudix (nucleoside diphosphate linked moiety X) type motif 14; Nudix motif 14; NUDT14; UDP sugar diphosphatase; UDPG pyrophosphatase; UGPP; UGPPase; Uridine diphosphate glucose pyrophosphatase.
Research Area	Cell biology  immunology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Cow, Horse, Sheep, Guinea Pig, )
Applications	WB=1:500-2000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	24kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human NUDT14: 1-100/222
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	UDP-glucose (UDPG) acts as the sugar donor in numerous glycosylation reactions, including those involved in the production of glycogen. NUDT14 is a UDPG pyrophosphatase (EC 3.6.1.45) that hydrolyzes UDPG to produce glucose 1-phosphate and UMP (Yagi et al., 2003 [PubMed 12429023]).[supplied by OMIM, Mar 2008] Function: Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and ADP-ribose to ribose 5-phosphate and AMP. The physiological substrate is probably UDP-glucose. Poor activity on other substrates such as ADP-glucose, CDP-glucose, GDP-glucose and GDP-mannose. Subcellular Location: Cytoplasm. Similarity: Belongs to the Nudix hydrolase family. Contains 1 nudix hydrolase domain. SWISS: O95848 Gene ID: 256281 Database links: Entrez Gene: 100126049 Cow Entrez Gene: 256281 Human Entrez Gene: 66174 Mouse Entrez Gene: 299346 Rat Omim: 609219 Human SwissProt: Q05B60 Cow SwissProt: O95848 Human SwissProt: Q9D142 Mouse Unigene: 526432 Human Unigene: 7070 Mouse
Product Picture	Sample: Lane 1: A549 (Human) Cell Lysate at 30 ug Lane 2: U87MG (Human) Cell Lysate at 30 ug Primary: Anti- NUDT14 (SL19511R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 24 kD Observed band size: 25 kD

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