Product Name	NUDT10
Chinese Name	NUDT10蛋白抗体
Alias	NUD10_HUMAN; Diphosphoinositol polyphosphate phosphohydrolase 3-alpha; DIPP-3-alpha; DIPP3-alpha; hDIPP3alpha; Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-alpha; AltName: Diadenosine hexaphosphate hydrolase (AMP-forming); AltName: Nucleoside diphosphate-linked moiety X motif 10; Nudix motif 10; hAps2.
Research Area	Cell biology  immunology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	18kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human NUDT10: 51-120/164
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	NUDT10 belongs to a subgroup of phosphohydrolases that preferentially attack diphosphoinositol polyphosphates (Hidaka et al., 2002 [PubMed 12105228]).[supplied by OMIM, Mar 2008] Function: Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate. Subcellular Location: Cytoplasm. Tissue Specificity: Mainly expressed in testis and, at lower level in brain. According to PubMed:12121577, it is widely expressed. Similarity: Belongs to the Nudix hydrolase family. DIPP subfamily. Contains 1 nudix hydrolase domain. SWISS: Q8NFP7 Gene ID: 170685 Database links: Entrez Gene: 170685 Human Entrez Gene: 616931 Cow Entrez Gene: 102954 Mouse Entrez Gene: 58242 Mouse Entrez Gene: 367747 Rat Omim: 300527 Human SwissProt: Q58CW0 Cow SwissProt: Q8NFP7 Human SwissProt: P0C027 Mouse Unigene: 375178 Human Unigene: 41198 Mouse Unigene: 426101 Mouse

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