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Product Name NT5C1B/RDH14 Chinese Name 胞浆5'核苷酸酶1B抗体 Alias 5' nucleotidase cytosolic IB; 5' nucleotidase cytosolic IB isoform CRA_b; 5NT1B_HUMAN; AIRP; Autoimmune infertility-related protein; CN IB; cN-IB; cN1B; CNIB; Cytosolic 5' nucleotidase 1B; Cytosolic 5' nucleotidase IB; Cytosolic 5'-nucleotidase 1B; Cytosolic 5'-nucleotidase IB; MGC26640; Nt5c1b 5' nucleotidase cytosolic IB; NT5C1B; Nt5c1b protein; Nucleotidase 5 prime cytosolic IB; Rdh14. Research Area Cell biology Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 69kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human NT5C1B: 1-100/610 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This locus represents naturally occurring read-through transcription between the neighboring NT5C1B (5'-nucleotidase, cytosolic IB) and RDH14 (retinol dehydrogenase 14) genes on chromosome 2. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with the products of each individual gene. [provided by RefSeq, Nov 2010]
Function:
Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Highly expressed in testis, placenta and pancreas. Detected at lower levels in heart, kidney, liver and lung.
Similarity:
Belongs to the 5'-nucleotidase type 3 family.
SWISS:
Q96P26
Gene ID:
100526794
Database links:Entrez Gene: 100526794 Human
Entrez Gene: 93034 Human
Entrez Gene: 70881 Mouse
Omim: 610526 Human
SwissProt: Q96P26 Human
SwissProt: Q91YE9 Mouse
Unigene: 120319 Human
Unigene: 272843 Mouse
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