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Product Name NSUN5P2 Chinese Name NSUN5P2蛋白抗体 Alias FLJ11626; MGC129801; MGC15057; NOL1/NOP2/Sun domain family member 5C; NOL1R2; NOP2/Sun domain family, member 5 pseudogene 2; NOP2/Sun domain family, member 5C (pseudogene); NOP2/Sun domain family, member 5C; NSUN5C; Putative methyltransferase NSUN5C; WBSCR20B; WBSCR20C; Williams-Beuren syndrome chromosomal region 20C protein. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 34kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human NSUN5P2: 231-315/315 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This locus represents a transcribed pseudogene of a nearby locus on chromosome 7, which encodes a putative methyltransferase. There is also a third closely related pseudogene locus in this region. There is extensive alternative splicing at this locus. [provided by RefSeq, Jul 2013]
Function:
May have S-adenosyl-L-methionine-dependent methyl-transferase activity.
Tissue Specificity:
Ubiquitous.
DISEASE:
NSUN5C is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region.
Similarity:
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
SWISS:
Q63ZY6
Gene ID:
260294
Database links:Entrez Gene: 260294 Human
SwissProt: Q63ZY6 Human
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